Bioscreen Immunospheres (Sperm Antibody Test)

SKU: FD-IGMA3
£320.00

Bioscreen Immunospheres (Sperm Antibody Test) - IgM is backordered and will ship as soon as it is back in stock.

Please reach out on the form below for lead time. 

Description

Bead Method for the Detection of Sperm-Reactive IgG Antibodies

Features

  • 100 determinations per reagent recommended as a replacement to the ImmunoBeads™ Test
  • Improvement over IBT- see comparison below
  • 18-month shelf life

Background Information

There is considerable evidence that antibodies directed against sperm surface antigens exert a fertility-reducing effect. When antisperm antibodies are present, they bind to the surface of the sperm. Such sperm-bound antibodies may impair sperm movement, penetration of the cumulus and/or zona pellucida, the acrosome reaction, interaction of sperm and egg as well as identify the sperm for destruction by the immune system.  It has also been suggested that sperm antibodies may exert an embryotoxic effect. Finally, there is evidence that antibody concentration is correlated directly with the severity of sperm functional impairment and inversely with potential fertilisability.

For these reasons, many reproductive specialists screen sperm and/or serum for anti-sperm antibodies before choosing an appropriate Assisted Reproductive Technology.

Product Specification

 Features ImmunoSpheres
Beads Mono-dispersed
Bead Size Uniform 3.0um latex beads
Bead Colour

Blue for Anti-IgG

Blue for Anti-IgA

Blue for Anti-IgM

Bead Preparation Wash each time
Microscopy Bright field of phase contrast
Shelf Life 18 months

Documents

Safety Data Sheet

Material Safety Data Sheet

Information For Use

 

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